|
|
[protein]-L-asparagine + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_diphosphate + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.99.18
dolichyl-diphosphooligosaccharide---protein glycotransferase
|
–
|
| |
KEGG:
R05976
|
|
|
|
2 UDP-galactose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn <=> 2 UDP + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
2.4.1.38
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
|
–
|
| |
KEGG:
R05989
|
|
|
|
dolichyl_diphosphate + H2O <=> dolichyl_phosphate + H+ + phosphate
|
3.6.1.43
dolichyldiphosphatase
|
–
|
| |
BRENDA:
BR29529
KEGG:
R01004
MetaCyc:
DOLICHYLDIPHOSPHATASE-RXN
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.143
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05985
|
|
|
|
dolichyl_phosphate + H2O <=> dolichol + phosphate
|
3.1.3.51
dolichyl-phosphatase
|
–
|
| |
BRENDA:
BR15945
KEGG:
R01003
MetaCyc:
DOLICHYL-PHOSPHATASE-RXN
|
|
|
|
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn + 2 H2O <=> beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn + 2 alpha-D-mannopyranose
|
3.2.1.114
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
|
–
|
| |
KEGG:
R05984
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.261
dolichyl-P-Man:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
|
–
|
| |
KEGG:
R06261
|
|
|
|
H2O + alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> D-glucose + alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
3.2.1.207
mannosyl-oligosaccharide alpha-1,3-glucosidase
|
–
|
| |
KEGG:
R05980
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->6)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.155
alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05991
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.260
dolichyl-P-Man:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
|
–
|
| |
KEGG:
R06260
|
|
|
|
GDP-mannose + beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> GDP + alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.132
GDP-Man:Man1GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase
|
–
|
| |
KEGG:
R05973
|
|
|
|
UDP-N-acetyl-D-glucosamine + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.101
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05983
|
|
|
|
UDP-glucose + dolichyl_phosphate <=> dolichyl_beta-D-glucosyl_phosphate + UDP
|
2.4.1.117
dolichyl-phosphate beta-glucosyltransferase
|
–
|
| |
BRENDA:
BR44147
KEGG:
R01005
MetaCyc:
2.4.1.117-RXN
SABIO-RK:
1297
|
|
|
|
GDP-mannose + diphosphodolichyl-N-acetyl-D-glucosaminyl-N-acetyl-D-glucosamine <=> beta-(1->4)-D-mannosylchitobiosyldiphosphodolichol + GDP + H+
|
2.4.1
2.4.1.142
chitobiosyldiphosphodolichol beta-mannosyltransferase
|
–
–
|
| |
BRENDA:
BR47411
KEGG:
R04331;
R04502;
R05972
MetaCyc:
2.4.1.142-RXN
|
|
|
|
Dolichyl_D-glucosyl_phosphate + alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.265
dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase
|
–
|
| |
KEGG:
R06263
|
|
|
|
dolichyl_beta-D-glucosyl_phosphate + H2O <=> dolichyl_phosphate + D-glucose + H+
|
3.1.4.48
dolichylphosphate-glucose phosphodiesterase
|
–
|
| |
BRENDA:
BR48168
KEGG:
R01006
MetaCyc:
3.1.4.48-RXN
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.258
dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase
|
–
|
| |
KEGG:
R06258
|
|
|
|
H2O + alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> D-glucose + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
3.2.1.207
mannosyl-oligosaccharide alpha-1,3-glucosidase
|
–
|
| |
KEGG:
R05981
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.145
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05987
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.259
dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
|
–
|
| |
KEGG:
R06259
|
|
|
|
H2O + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> beta-D-glucose + alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
3.2.1.106
mannosyl-oligosaccharide glucosidase
|
–
|
| |
KEGG:
R05979
|
|
|
|
N-acetyl-D-glucosaminyl-diphosphodolichol + UDP-N-acetyl-D-glucosamine <=> diphosphodolichyl-N-acetyl-D-glucosaminyl-N-acetyl-D-glucosamine + H+ + UDP
|
2.4.1.141
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase
|
–
|
| |
BRENDA:
BR47648
KEGG:
R04494;
R05970
MetaCyc:
2.4.1.141-RXN
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->6)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->6)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.201
alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05992
|
|
|
|
UDP-N-acetyl-D-glucosamine + dolichyl_phosphate <=> N-acetyl-D-glucosaminyl-diphosphodolichol + UMP
|
2.7.8.15
UDP-N-acetylglucosamine---dolichyl-phosphate N-acetylglucosaminephosphotransferase
|
–
|
| |
BRENDA:
BR48090
KEGG:
R01007;
R05969
MetaCyc:
2.7.8.15-RXN
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-[beta-D-GlcNAc-(1->4)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.144
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05986
|
|
|
|
2 CMP-N-acetylneuraminate + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn <=> 2 CMP + DS_3
|
2.4.99.1
beta-galactoside alpha-(2,6)-sialyltransferase
|
–
|
| |
KEGG:
R05990
|
|
|
|
alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol + GDP-mannose <=> alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol + GDP
|
2.4.1.131
GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
|
–
|
| |
KEGG:
R06128
|
|
|
|
dolichol + NADP+ <=> di-trans,_poly-cis-polyprenol + NADPH + H+
|
1.3.1.94
polyprenol reductase
1.3.1.B13
|
–
–
|
| |
BRENDA:
BR50150;
BR51446
KEGG:
R12299
MetaCyc:
RXN-9971
|
|
|
|
GDP-mannose + alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> GDP + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.257
GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
|
–
|
| |
KEGG:
R06238
|
|
|
|
alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn + 3 H2O <=> alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn + 3 D-mannose
|
3.2.1.113
mannosyl-oligosaccharide 1,2-alpha-mannosidase
|
–
|
| |
KEGG:
R12479
|
|
|
|
GDP-L-fucose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> GDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
2.4.1.68
glycoprotein 6-alpha-L-fucosyltransferase
|
–
|
| |
KEGG:
R05988
|
|
|
|
dolichol + CTP <=> dolichyl_phosphate + H+ + CDP
|
2.7.1.108
dolichol kinase
|
–
|
| |
BRENDA:
BR47722
KEGG:
R01018
MetaCyc:
DOLICHOL-KINASE-RXN
|
|
|
|
Dolichyl_D-glucosyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.267
dolichyl-P-Glc:Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase
|
–
|
| |
KEGG:
R06262
|
|
|
|
Dolichyl_D-glucosyl_phosphate + alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1
2.4.1.256
dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol alpha-1,2-glucosyltransferase
|
–
–
|
| |
KEGG:
R06264
|
|
|
|
GDP-mannose + dolichyl_phosphate <=> dolichyl_phosphate_D-mannose + GDP
|
2.4.1.54
undecaprenyl-phosphate mannosyltransferase
2.4.1.83
dolichyl-phosphate beta-D-mannosyltransferase
|
–
–
|
| |
BRENDA:
BR44254
KEGG:
R01009
MetaCyc:
2.4.1.83-RXN
SABIO-RK:
1301
|
|
|
|
H2O + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
3.2.1.209
endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase
|
–
|
| |
KEGG:
R06722
|
|
|
|
alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol + GDP-mannose <=> alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol + GDP
|
2.4.1.131
GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
|
–
|
| |
KEGG:
R06127
|
|
